estrodiol - Trusted Medicine - Misspelled Drug Names



estrodiol

Estrodiol - a means of hormone replacement therapy estrogen deficiency (disease or pathological states, based on a lack of elaboration of endogenous female sex hormones). Among these states, on the one hand, are climacteric syndrome - syndrome, with age declining ovarian endocrine function, and on the other - a deficit estrogen after rapid removal of the ovaries or radiation castration. In both cases reducing endogenic estrogen leads to the development of tidal, sweating, sleep disorders, depressive states, irritability, headaches, dizziness, skin atrophic processes and mucous membranes, bladder, etc. In addition, the delayed effects estrogen deficiency include the development of osteoporosis (especially menopausal osteoporosis), as well as an increased risk of cardiovascular disease (myocardial infarction, cerebral stroke) in connection with the development of atherosclerotic vascular lesions. By participating in the realization of the positive and negative feedback HYPOTHALAMIC-HYPOPHYSIAL-ovarian system, estrodiol is capable of causing moderate and expressed the central effects normalize mood. Normalizing effect of estrodiol on lipid metabolism, reflected in increasing levels in blood plasma high density lipoproteins, while lowering low-density lipoproteins, in contrast to the development of atherosclerotic process, hence reducing the risk of developing cardiovascular disease among older women. Plaster estrodiol placed on the skin. Slow allocation of estrodiol through the membrane plaster supports therapeutic concentration in the blood within 3-4 days.

Indications
Estrogen deficiency in menopause and after physiological, premature menopause, vasomotor violations, mental violations (asthenia, sleep disorders, depression); prevention of osteoporosis and cardiovascular disease among women perimenopause period; delayed puberty in girls; alopecia; weakness of generic activities; Primary biliarny cirrhosis among women; Breast cancer in men and women with metastases; carcinoma of the prostate (palliative therapy).

Side Effects
These symptoms tend to be transitory in nature. Headache, dizziness, depression, migraine, chorea, a violation of (changing curvature of the cornea). Increased blood pressure. Nausea, vomiting, flatulence, cholestatic hepatitis, Changes in the nature of vaginal discharge, change in libido, uterine bleeding (signs of overdose estradiol) Endometrial hyperplasia, an increase in the size of the uterus, fibrotic changes Myometrium, vaginal candidiasis (in the appointment of the drug without combination with progesterone). In the first months of treatment may mark the pain of mammary glands, seal and breast enlargement. Edema, increasing or reducing body weight, lower tolerance to carbohydrates. In the long application in rare cases, sensitive to ultraviolet women face in the skin may appear Pigmented spots, increased while in the sun.



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